Generalised bullous fixed drug eruption masquerading as toxic epidermal necrolysis
نویسندگان
چکیده
منابع مشابه
Drug-induced linear IgA bullous dermatosis simulating toxic epidermal necrolysis.
Linear IgA bullous dermatosis (LAD) is an autoimmune subepidermal blistering disorder. LAD may be either idiopathic or drug related; the most common drug being vancomycin. The clinical presentations of both idiopathic and drug-related LAD are variable and may mimic other blistering disorders. We report a case of a 76-year-old man known to have a renal cell carcinoma who presented a vancomycin-i...
متن کاملLinear IgA Bullous Dermatosis Presenting as Toxic Epidermal Necrolysis.
dehiscence. Closure is performed by tissue planes, with a V-Y suture. Close follow-up is required in the immediate postoperative period, with regular wound care. The cosmetic result of the double hatchet flap can be excellent, as tissue of similar characteristics is used, with preservation of hair, texture, and thickness,3 rapid healing, and minimal scarring and comorbidity. Possible complicati...
متن کاملNonpigmenting fixed drug eruption as a possible abortive variant of toxic epidermal necrolysis: immunohistochemical and serum cytokine analyses.
Nonpigmenting fixed drug eruption (NPFDE) is clinically indistinguishable from Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) in its initial presentation. The traditional paradigm that epidermal changes are absent in NPFDE cannot be easily reconciled with the clinical resemblance to SJS/TEN. We therefore investigated whether NPFDE is pathogenetically different from pigmented...
متن کاملVancomycin-associated linear IgA bullous dermatosis mimicking toxic epidermal necrolysis.
Vancomycin is the most frequent trigger of drug-induced linear IgA bullous dermatosis. We describe a fulminant case of linear IgA bullous dermatosis in a 74-year-old man who experienced skin sloughing of 90% of his body surface after receiving vancomycin.
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1. Vincent SD, Fotos PG, Baker KA, Williams TP. Oral lichen planus: The clinical, histological and therapeutic features of 100 cases. Oral Surg Oral Med Oral Pathol 1990;70:165-71. 2. Eisen D. The evaluation of cutaneous, genital, scalp, nail, esophageal, and ocular involvement in patients with oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999;91:431-6. 3. Van der Meij E...
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ژورنال
عنوان ژورنال: Our Dermatology Online
سال: 2020
ISSN: 2081-9390
DOI: 10.7241/ourd.2020s3.7